Hypoxia, mitochondrial dysfunction and synovial invasiveness in rheumatoid arthritis
Hypoxia, mitochondrial dysfunction and synovial invasiveness in rheumatoid arthritis
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
Hypoxia, arising as a consequence of the increased cellular demand for oxygen during the inflammatory response, is a powerful trigger for the activation, proliferation and survival of endothelial cells and fibroblast-like synoviocytes
Impaired mitochondrial function and oxidative damage caused by hypoxia further exacerbate the infl...
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Full title
Hypoxia, mitochondrial dysfunction and synovial invasiveness in rheumatoid arthritis
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TN_cdi_proquest_miscellaneous_1799562286
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1799562286
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ISSN
1759-4790
E-ISSN
1759-4804
DOI
10.1038/nrrheum.2016.69
