Safety and efficacy of subcutaneous tocilizumab in adults with systemic sclerosis (faSScinate): a ph...
Safety and efficacy of subcutaneous tocilizumab in adults with systemic sclerosis (faSScinate): a phase 2, randomised, controlled trial
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Author / Creator
Khanna, Dinesh, Prof , Denton, Christopher P, Prof , Jahreis, Angelika, MD , van Laar, Jacob M, Prof , Frech, Tracy M, MD , Anderson, Marina E, FRCP , Baron, Murray, MD , Chung, Lorinda, MD , Fierlbeck, Gerhard, MD , Lakshminarayanan, Santhanam, MD , Allanore, Yannick, Prof , Pope, Janet E, MD , Riemekasten, Gabriela, Prof , Steen, Virginia, Prof , Müller-Ladner, Ulf, Prof , Lafyatis, Robert, MD , Stifano, Giuseppina, MD , Spotswood, Helen, PhD , Chen-Harris, Haiyin, PhD , Dziadek, Sebastian, PhD , Morimoto, Alyssa, PhD , Sornasse, Thierry, PhD , Siegel, Jeffrey, MD and Furst, Daniel E, Prof
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
England: Elsevier Ltd
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Scope and Contents
Contents
Summary Background Systemic sclerosis is a rare disabling autoimmune disease with few treatment options. The efficacy and safety of tocilizumab, an interleukin 6 receptor-α inhibitor, was assessed in the faSScinate phase 2 trial in patients with systemic sclerosis. Methods We did this double-blind, placebo-controlled study at 35 hospitals in Canada...
Alternative Titles
Full title
Safety and efficacy of subcutaneous tocilizumab in adults with systemic sclerosis (faSScinate): a phase 2, randomised, controlled trial
Authors, Artists and Contributors
Author / Creator
Denton, Christopher P, Prof
Jahreis, Angelika, MD
van Laar, Jacob M, Prof
Frech, Tracy M, MD
Anderson, Marina E, FRCP
Baron, Murray, MD
Chung, Lorinda, MD
Fierlbeck, Gerhard, MD
Lakshminarayanan, Santhanam, MD
Allanore, Yannick, Prof
Pope, Janet E, MD
Riemekasten, Gabriela, Prof
Steen, Virginia, Prof
Müller-Ladner, Ulf, Prof
Lafyatis, Robert, MD
Stifano, Giuseppina, MD
Spotswood, Helen, PhD
Chen-Harris, Haiyin, PhD
Dziadek, Sebastian, PhD
Morimoto, Alyssa, PhD
Sornasse, Thierry, PhD
Siegel, Jeffrey, MD
Furst, Daniel E, Prof
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1800701068
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1800701068
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(16)00232-4