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Cucurbitacin B reverses multidrug resistance by targeting CIP2A to reactivate protein phosphatase 2A...

Cucurbitacin B reverses multidrug resistance by targeting CIP2A to reactivate protein phosphatase 2A...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1801427651

Cucurbitacin B reverses multidrug resistance by targeting CIP2A to reactivate protein phosphatase 2A in MCF-7/Adriamycin cells

About this item

Full title

Cucurbitacin B reverses multidrug resistance by targeting CIP2A to reactivate protein phosphatase 2A in MCF-7/Adriamycin cells

Publisher

Greece: D.A. Spandidos

Journal title

Oncology reports, 2016-08, Vol.36 (2), p.1180-1186

Language

English

Formats

Publication information

Publisher

Greece: D.A. Spandidos

More information

Scope and Contents

Contents

Cancerous inhibitor of protein phosphatase 2A (CIP2A) is a human oncoprotein that is overexpressed in various tumors. A previous study found that CIP2A expression is associated with doxorubicin (Dox) resistance. In the present study, we investigated whether cucurbitacin B (CuB), a natural anticancer compound found in Cucurbitaceae, reversed multidr...

Alternative Titles

Full title

Cucurbitacin B reverses multidrug resistance by targeting CIP2A to reactivate protein phosphatase 2A in MCF-7/Adriamycin cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1801427651

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1801427651

Other Identifiers

ISSN

1021-335X

E-ISSN

1791-2431

DOI

10.3892/or.2016.4892

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