De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
NF-κB transcription factors mediate the effects of pro-inflammatory cytokines such as tumour necrosis factor-α and interleukin-1β
1
. Failure to downregulate NF-κB transcriptional activity results in chronic inflammation and cell death, as observed in
A20
-deficient mice
2
. A20 is a potent inhibitor of NF-κB signalling, but its m...
Alternative Titles
Full title
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_18022498
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_18022498
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature02794
