Herpes Simplex Virus Type-1 Induces IFN-α Production via Toll-Like Receptor 9-Dependent and -Indepen...
Herpes Simplex Virus Type-1 Induces IFN-α Production via Toll-Like Receptor 9-Dependent and -Independent Pathways
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Type I IFN production in response to the DNA virus herpes simplex virus type-1 (HSV-1) is essential in controlling viral replication. We investigated whether plasmacytoid dendritic cells (pDC) were the major tissue source of IFN-α, and whether the production of IFN-α in response to HSV-1 depended on Toll-like receptor 9 (TLR9). Total spleen cells o...
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Full title
Herpes Simplex Virus Type-1 Induces IFN-α Production via Toll-Like Receptor 9-Dependent and -Independent Pathways
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TN_cdi_proquest_miscellaneous_18023935
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_18023935
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0403555101
