Genetic activation of BK currents in vivo generates bidirectional effects on neuronal excitability
Genetic activation of BK currents in vivo generates bidirectional effects on neuronal excitability
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Large-conductance calcium-activated potassium channels (BK) are potent negative regulators of excitability in neurons and muscle, and increasing BK current is a novel therapeutic strategy for neuro- and cardioprotection, disorders of smooth muscle hyperactivity, and several psychiatric diseases. However, in some neurons, enhanced BK current is link...
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Full title
Genetic activation of BK currents in vivo generates bidirectional effects on neuronal excitability
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TN_cdi_proquest_miscellaneous_1803081581
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803081581
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1205573109
