Structural insight into HIV-1 capsid recognition by rhesus TRIM5α
Structural insight into HIV-1 capsid recognition by rhesus TRIM5α
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Tripartite motif protein isoform 5 alpha (TRIM5α) is a potent antiviral protein that restricts infection by HIV-1 and other retroviruses. TRIM5α recognizes the lattice of the retrovirus capsid through its B30.2 (PRY/SPRY) domain in a species-specific manner. Upon binding, TRIM5α induces premature disassembly of the viral capsid and activates the do...
Alternative Titles
Full title
Structural insight into HIV-1 capsid recognition by rhesus TRIM5α
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Record Identifier
TN_cdi_proquest_miscellaneous_1803081904
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803081904
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1210903109
