Dimerization of LTβR by LTα₁β₂ is necessary and sufficient for signal transduction
Dimerization of LTβR by LTα₁β₂ is necessary and sufficient for signal transduction
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Publisher
United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Homotrimeric TNF superfamily ligands signal by inducing trimers of their cognate receptors. As a biologically active heterotrimer, Lymphotoxin(LT)α ₁β ₂ is unique in the TNF superfamily. How the three unique potential receptor-binding interfaces in LTα ₁β ₂ trigger signaling via LTβ Receptor (LTβR) resulting in lymphoid organogenesis and propagatio...
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Full title
Dimerization of LTβR by LTα₁β₂ is necessary and sufficient for signal transduction
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TN_cdi_proquest_miscellaneous_1803085277
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803085277
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1310838110
