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Zinc-finger antiviral protein mediates retinoic acid inducible gene I—like receptor-independent anti...

Zinc-finger antiviral protein mediates retinoic acid inducible gene I—like receptor-independent anti...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803093061

Zinc-finger antiviral protein mediates retinoic acid inducible gene I—like receptor-independent antiviral response to murine leukemia virus

About this item

Full title

Zinc-finger antiviral protein mediates retinoic acid inducible gene I—like receptor-independent antiviral response to murine leukemia virus

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (30), p.12379-12384

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

When host cells are infected by an RNA virus, pattern-recognition receptors (PRRs) recognize the viral RNA and induce the antiviral innate immunity. Toll-like receptor 7 (TLR7) detects the genomic RNA of incoming murine leukemia virus (MLV) in endosomes and mediates the antiviral response. However, the RNA-sensing PRR that recognizes the MLV in the...

Alternative Titles

Full title

Zinc-finger antiviral protein mediates retinoic acid inducible gene I—like receptor-independent antiviral response to murine leukemia virus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1803093061

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803093061

Other Identifiers

ISSN

0027-8424,1091-6490

E-ISSN

1091-6490

DOI

10.1073/pnas.1310604110

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