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Serial propagation of distinct strains of Aβ prions from Alzheimer’s disease patients

Serial propagation of distinct strains of Aβ prions from Alzheimer’s disease patients

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803094371

Serial propagation of distinct strains of Aβ prions from Alzheimer’s disease patients

About this item

Full title

Serial propagation of distinct strains of Aβ prions from Alzheimer’s disease patients

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (28), p.10323-10328

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

An increasing number of studies argues that self-propagating protein conformations (i.e., prions) feature in the pathogenesis of several common neurodegenerative diseases. Mounting evidence contends that aggregates of the amyloid-β (Aβ) peptide become self-propagating in Alzheimer’s disease (AD) patients. An important characteristic of prions is th...

Alternative Titles

Full title

Serial propagation of distinct strains of Aβ prions from Alzheimer’s disease patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1803094371

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803094371

Other Identifiers

ISSN

0027-8424,1091-6490

E-ISSN

1091-6490

DOI

10.1073/pnas.1408900111

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