Serial propagation of distinct strains of Aβ prions from Alzheimer’s disease patients
Serial propagation of distinct strains of Aβ prions from Alzheimer’s disease patients
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
An increasing number of studies argues that self-propagating protein conformations (i.e., prions) feature in the pathogenesis of several common neurodegenerative diseases. Mounting evidence contends that aggregates of the amyloid-β (Aβ) peptide become self-propagating in Alzheimer’s disease (AD) patients. An important characteristic of prions is th...
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Full title
Serial propagation of distinct strains of Aβ prions from Alzheimer’s disease patients
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TN_cdi_proquest_miscellaneous_1803094371
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803094371
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ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1408900111