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Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis...

Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803109379

Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice

About this item

Full title

Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-05, Vol.110 (21), p.8674-8679

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Deep vein thrombosis and pulmonary embolism are major health problems associated with high mortality. Recently, DNA-based neutrophil extracellular traps (NETs) resulting from the release of decondensed chromatin, were found to be part of the thrombus scaffold and to promote coagulation. However, the significance of nuclear decondensation and NET ge...

Alternative Titles

Full title

Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1803109379

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803109379

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1301059110

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