Log in to save to my catalogue

Use of mutant ¹²⁵I-Perfringolysin O to probe transport and organization of cholesterol in membranes...

Use of mutant ¹²⁵I-Perfringolysin O to probe transport and organization of cholesterol in membranes...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803109922

Use of mutant ¹²⁵I-Perfringolysin O to probe transport and organization of cholesterol in membranes of animal cells

About this item

Full title

Use of mutant ¹²⁵I-Perfringolysin O to probe transport and organization of cholesterol in membranes of animal cells

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (26), p.10580-10585

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Animal cells strictly control the distribution of cholesterol in their organelle membranes. This regulation requires an efficient machinery to transport insoluble cholesterol between organelles. In the present study, we generate an ¹²⁵I-labeled mutant version of Perfringolysin O (PFO), a cholesterol-binding protein, and use it to measure cholestero...

Alternative Titles

Full title

Use of mutant ¹²⁵I-Perfringolysin O to probe transport and organization of cholesterol in membranes of animal cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1803109922

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803109922

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1309273110

How to access this item