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Blockade of A₂A receptors potently suppresses the metastasis of CD73⁺ tumors

Blockade of A₂A receptors potently suppresses the metastasis of CD73⁺ tumors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803111967

Blockade of A₂A receptors potently suppresses the metastasis of CD73⁺ tumors

About this item

Full title

Blockade of A₂A receptors potently suppresses the metastasis of CD73⁺ tumors

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (36), p.14711-14716

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

CD73 inhibits antitumor immunity through the activation of adenosine receptors expressed on multiple immune subsets. CD73 also enhances tumor metastasis, although the nature of the immune subsets and adenosine receptor subtypes involved in this process are largely unknown. In this study, we revealed that A ₂A/A ₂B receptor antagonists were effectiv...

Alternative Titles

Full title

Blockade of A₂A receptors potently suppresses the metastasis of CD73⁺ tumors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1803111967

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803111967

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1308209110

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