Metalloproteases meprin α and meprin β are C- and N-procollagen proteinases important for collagen a...
Metalloproteases meprin α and meprin β are C- and N-procollagen proteinases important for collagen assembly and tensile strength
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Type I fibrillar collagen is the most abundant protein in the human body, crucial for the formation and strength of bones, skin, and tendon. Proteolytic enzymes are essential for initiation of the assembly of collagen fibrils by cleaving off the propeptides. We report that Mep1a ⁻/⁻ and Mep1b ⁻/⁻ mice revealed lower amounts of mature collagen I com...
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Full title
Metalloproteases meprin α and meprin β are C- and N-procollagen proteinases important for collagen assembly and tensile strength
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TN_cdi_proquest_miscellaneous_1803112514
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803112514
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1305464110
