GABAB autoreceptor-mediated cell type-specific reduction of inhibition in epileptic mice
GABAB autoreceptor-mediated cell type-specific reduction of inhibition in epileptic mice
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Publisher
Washington, DC: National Academy of Sciences
Journal title
Language
English
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Publisher
Washington, DC: National Academy of Sciences
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Contents
GABA B receptors (GABA BRs) mediate slow inhibitory effects on neuronal excitability and synaptic transmission in the brain. However, the GABA BR agonist baclofen can also promote excitability and seizure generation in human patients and animals models. Here we show that baclofen has concentration-dependent effects on the hippocampal network in a m...
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Full title
GABAB autoreceptor-mediated cell type-specific reduction of inhibition in epileptic mice
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Record Identifier
TN_cdi_proquest_miscellaneous_1803116519
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803116519
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1313505110
