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Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9

Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803117295

Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9

About this item

Full title

Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (47), p.19012-19017

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The ability to engineer genomes in a specific, systematic, and cost-effective way is critical for functional genomic studies. Recent advances using the CRISPR-associated single-guide RNA system (Cas9/sgRNA) illustrate the potential of this simple system for genome engineering in a number of organisms. Here we report an effective and inexpensive met...

Alternative Titles

Full title

Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1803117295

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803117295

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1318481110

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