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Phosphoproteomic analysis identifies the tumor suppressor PDCD4 as a RSK substrate negatively regula...

Phosphoproteomic analysis identifies the tumor suppressor PDCD4 as a RSK substrate negatively regula...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803134238

Phosphoproteomic analysis identifies the tumor suppressor PDCD4 as a RSK substrate negatively regulated by 14-3-3

About this item

Full title

Phosphoproteomic analysis identifies the tumor suppressor PDCD4 as a RSK substrate negatively regulated by 14-3-3

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (29), p.10402-10402

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The RSK family is a group of Ser/Thr kinases that promotes cell growth and proliferation in response to the Ras/MAPK pathway. Deregulated RSK activity has been associated with different disorders and diseases, such as cancer, but relatively little is known regarding the contribution of RSK to tumorigenesis. In this study, we describe, to our knowle...

Alternative Titles

Full title

Phosphoproteomic analysis identifies the tumor suppressor PDCD4 as a RSK substrate negatively regulated by 14-3-3

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1803134238

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803134238

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1405601111

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