Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to...
Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial
About this item
Full title
Author / Creator
Wenzel, Sally, Prof , Castro, Mario, MD , Corren, Jonathan, MD , Maspero, Jorge, MD , Wang, Lin, PhD , Zhang, Bingzhi, PhD , Pirozzi, Gianluca, MD , Sutherland, E Rand, MD , Evans, Robert R, PharmD , Joish, Vijay N, PhD , Eckert, Laurent, PhD , Graham, Neil M H, MD , Stahl, Neil, PhD , Yancopoulos, George D, MD , Louis-Tisserand, Mariana, MD and Teper, Ariel, MD
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
England: Elsevier Ltd
Subjects
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Scope and Contents
Contents
Summary Background Dupilumab, a fully human anti-interleukin-4 receptor α monoclonal antibody, inhibits interleukin-4 and interleukin-13 signalling, key drivers of type-2-mediated inflammation. Adults with uncontrolled persistent asthma who are receiving medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist require additional tr...
Alternative Titles
Full title
Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial
Authors, Artists and Contributors
Author / Creator
Castro, Mario, MD
Corren, Jonathan, MD
Maspero, Jorge, MD
Wang, Lin, PhD
Zhang, Bingzhi, PhD
Pirozzi, Gianluca, MD
Sutherland, E Rand, MD
Evans, Robert R, PharmD
Joish, Vijay N, PhD
Eckert, Laurent, PhD
Graham, Neil M H, MD
Stahl, Neil, PhD
Yancopoulos, George D, MD
Louis-Tisserand, Mariana, MD
Teper, Ariel, MD
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1803452960
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1803452960
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(16)30307-5
