Regulatory T Cells Increase the Avidity of Primary CD8⁺ T Cell Responses and Promote Memory
Regulatory T Cells Increase the Avidity of Primary CD8⁺ T Cell Responses and Promote Memory
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Washington, DC: American Association for the Advancement of Science
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Language
English
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Washington, DC: American Association for the Advancement of Science
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Contents
Although regulatory T cells (T regs ) are known to suppress self-reactive autoimmune responses, their role during T cell responses to nonself antigens is not well understood. We show that T regs play a critical role during the priming of immune responses in mice. T reg depletion induced the activation and expansion of a population of low-avidity CD...
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Full title
Regulatory T Cells Increase the Avidity of Primary CD8⁺ T Cell Responses and Promote Memory
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TN_cdi_proquest_miscellaneous_1808087800
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1808087800
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1227049
