TLR13 Recognizes Bacterial 23S rRNA Devoid of Erythromycin Resistance—Forming Modification
TLR13 Recognizes Bacterial 23S rRNA Devoid of Erythromycin Resistance—Forming Modification
About this item
Full title
Author / Creator
Oldenburg, Marina , Krüger, Anne , Ferstl, Ruth , Kaufmann, Andreas , Nees, Gernot , Sigmund, Anna , Bathke, Barbara , Lauterbach, Henning , Suter, Mark , Dreher, Stefan , Koedel, Uwe , Akira, Shizuo , Kawai, Taro , Buer, Jan , Wagner, Hermann , Bauer, Stefan , Hochrein, Hubertus and Kirschning, Carsten J.
Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
Washington, DC: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Host protection from infection relies on the recognition of pathogens by innate pattern-recognition receptors such as Toll-like receptors (TLRs). Here, we show that the orphan receptor TLR13 in mice recognizes a conserved 23S ribosomal RNA (rRNA) sequence that is the binding site of macrolide, lincosamide, and streptogramin group (MLS) antibiotics...
Alternative Titles
Full title
TLR13 Recognizes Bacterial 23S rRNA Devoid of Erythromycin Resistance—Forming Modification
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1808094658
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1808094658
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1220363
