Immunogenicity and safety of a tetravalent E. coli O-antigen bioconjugate vaccine in animal models
Immunogenicity and safety of a tetravalent E. coli O-antigen bioconjugate vaccine in animal models
About this item
Full title
Author / Creator
Publisher
Netherlands: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Netherlands: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
Highlights • An ExPEC vaccine (O1, O2, O6, O25) was made using a novel bioconjugation process. • The 4-valent bioconjugated ExPEC vaccine was immunogenic in 3 animal models. • Antibody persistence and boostability were demonstrated in rats. • ExPEC-4V at full human dose was at the no observed adverse effect level in rats.
Alternative Titles
Full title
Immunogenicity and safety of a tetravalent E. coli O-antigen bioconjugate vaccine in animal models
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1808644911
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1808644911
Other Identifiers
ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2016.06.067
