GFI1 as a novel prognostic and therapeutic factor for AML/MDS
GFI1 as a novel prognostic and therapeutic factor for AML/MDS
About this item
Full title
Author / Creator
Hönes, J M , Botezatu, L , Helness, A , Vadnais, C , Vassen, L , Robert, F , Hergenhan, S M , Thivakaran, A , Schütte, J , Al-Matary, Y S , Lams, R F , Fraszscak, J , Makishima, H , Radivoyevitch, T , Przychodzen, B , da Conceição Castro, S V , Görgens, A , Giebel, B , Klein-Hitpass, L , Lennartz, K , Heuser, M , Thiede, C , Ehninger, G , Dührsen, U , Maciejewski, J P , Möröy, T and Khandanpour, C
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Genetic and epigenetic aberrations contribute to the initiation and progression of acute myeloid leukemia (AML). GFI1, a zinc-finger transcriptional repressor, exerts its function by recruiting histone deacetylases to target genes. We present data that low expression of
GFI1
is associated with an inferior prognosis of AML patients. To elucida...
Alternative Titles
Full title
GFI1 as a novel prognostic and therapeutic factor for AML/MDS
Authors, Artists and Contributors
Author / Creator
Botezatu, L
Helness, A
Vadnais, C
Vassen, L
Robert, F
Hergenhan, S M
Thivakaran, A
Schütte, J
Al-Matary, Y S
Lams, R F
Fraszscak, J
Makishima, H
Radivoyevitch, T
Przychodzen, B
da Conceição Castro, S V
Görgens, A
Giebel, B
Klein-Hitpass, L
Lennartz, K
Heuser, M
Thiede, C
Ehninger, G
Dührsen, U
Maciejewski, J P
Möröy, T
Khandanpour, C
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1808671971
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1808671971
Other Identifiers
ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/leu.2016.11
