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GGNBP2 acts as a tumor suppressor by inhibiting estrogen receptor α activity in breast cancer cells

GGNBP2 acts as a tumor suppressor by inhibiting estrogen receptor α activity in breast cancer cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1808706786

GGNBP2 acts as a tumor suppressor by inhibiting estrogen receptor α activity in breast cancer cells

About this item

Full title

GGNBP2 acts as a tumor suppressor by inhibiting estrogen receptor α activity in breast cancer cells

Publisher

New York: Springer US

Journal title

Breast cancer research and treatment, 2016-07, Vol.158 (2), p.263-276

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Gametogenetin-binding protein 2 (GGNBP2) is encoded in human chromosome 17q12-q23, a region known as a breast and ovarian cancer susceptibility locus. GGNBP2, also referred to ZFP403, has a single C2H2 zinc finger and a consensus LxxLL nuclear receptor-binding motif. Here, we demonstrate that
GGNBP2
expression is reduced in primary human brea...

Alternative Titles

Full title

GGNBP2 acts as a tumor suppressor by inhibiting estrogen receptor α activity in breast cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1808706786

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1808706786

Other Identifiers

ISSN

0167-6806

E-ISSN

1573-7217

DOI

10.1007/s10549-016-3880-2

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