CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes
CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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CRISPR knockout screens outperform shRNA and CRISPR-interference screens in a side-by-side comparison.
High-throughput genetic screens have become essential tools for studying a wide variety of biological processes. Here we experimentally compare systems based on clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated...
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CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes
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TN_cdi_proquest_miscellaneous_1808726189
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1808726189
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.3536