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CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes

CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1808726189

CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes

About this item

Full title

CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes

Publisher

New York: Nature Publishing Group US

Journal title

Nature biotechnology, 2016-06, Vol.34 (6), p.631-633

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

CRISPR knockout screens outperform shRNA and CRISPR-interference screens in a side-by-side comparison.
High-throughput genetic screens have become essential tools for studying a wide variety of biological processes. Here we experimentally compare systems based on clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated...

Alternative Titles

Full title

CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1808726189

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1808726189

Other Identifiers

ISSN

1087-0156

E-ISSN

1546-1696

DOI

10.1038/nbt.3536

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