Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults
Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults
About this item
Full title
Author / Creator
Yasuda, Takahiko , Tsuzuki, Shinobu , Kawazu, Masahito , Hayakawa, Fumihiko , Kojima, Shinya , Ueno, Toshihide , Imoto, Naoto , Kohsaka, Shinji , Kunita, Akiko , Doi, Koichiro , Sakura, Toru , Yujiri, Toshiaki , Kondo, Eisei , Fujimaki, Katsumichi , Ueda, Yasunori , Aoyama, Yasutaka , Ohtake, Shigeki , Takita, Junko , Sai, Eirin , Taniwaki, Masafumi , Kurokawa, Mineo , Morishita, Shinichi , Fukayama, Masashi , Kiyoi, Hitoshi , Miyazaki, Yasushi , Naoe, Tomoki and Mano, Hiroyuki
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Hiroyuki Mano and colleagues report fusions involving
DUX4
in 16.4% of Ph-negative adolescent and young adult acute lymphoblastic leukemia (AYA-ALL) cases. Transplantation assays in mice support an oncogenic role for the
DUX4-IGH
fusion gene, which expresses DUX4 protein with an aberrant C terminus at high levels in patients with AYA-AL...
Alternative Titles
Full title
Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults
Authors, Artists and Contributors
Author / Creator
Tsuzuki, Shinobu
Kawazu, Masahito
Hayakawa, Fumihiko
Kojima, Shinya
Ueno, Toshihide
Imoto, Naoto
Kohsaka, Shinji
Kunita, Akiko
Doi, Koichiro
Sakura, Toru
Yujiri, Toshiaki
Kondo, Eisei
Fujimaki, Katsumichi
Ueda, Yasunori
Aoyama, Yasutaka
Ohtake, Shigeki
Takita, Junko
Sai, Eirin
Taniwaki, Masafumi
Kurokawa, Mineo
Morishita, Shinichi
Fukayama, Masashi
Kiyoi, Hitoshi
Miyazaki, Yasushi
Naoe, Tomoki
Mano, Hiroyuki
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1808740154
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1808740154
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.3535
