Genotype–phenotype correlations in 5-fluorouracil metabolism: a candidate DPYD haplotype to improve...
Genotype–phenotype correlations in 5-fluorouracil metabolism: a candidate DPYD haplotype to improve toxicity prediction
About this item
Full title
Author / Creator
Gentile, G , Botticelli, A , Lionetto, L , Mazzuca, F , Simmaco, M , Marchetti, P and Borro, M
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
5-Fluorouracil is among the most widely used anticancer drug, but a fraction of treated patients develop severe toxicity, with potentially lethal injuries. The predictive power of the available pretreatment assays, used to identify patients at risk of severe toxicity, needs improvements. This study aimed to correlate a phenotypic marker of 5-fluoro...
Alternative Titles
Full title
Genotype–phenotype correlations in 5-fluorouracil metabolism: a candidate DPYD haplotype to improve toxicity prediction
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1811880296
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1811880296
Other Identifiers
ISSN
1470-269X
E-ISSN
1473-1150
DOI
10.1038/tpj.2015.56
