CD69 controls the uptake of L-tryptophan through LAT1-CD98 and AhR-dependent secretion of IL-22 in p...
CD69 controls the uptake of L-tryptophan through LAT1-CD98 and AhR-dependent secretion of IL-22 in psoriasis
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Author / Creator
Cibrian, Danay , Saiz, María Laura , de la Fuente, Hortensia , Sánchez-Díaz, Raquel , Moreno-Gonzalo, Olga , Jorge, Inmaculada , Ferrarini, Alessia , Vázquez, Jesús , Punzón, Carmen , Fresno, Manuel , Vicente-Manzanares, Miguel , Daudén, Esteban , Fernández-Salguero, Pedro M , Martín, Pilar and Sánchez-Madrid, Francisco
Publisher
New York: Nature Publishing Group US
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English
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Publisher
New York: Nature Publishing Group US
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Sanchez-Madrid and colleagues show that CD69 associates with the amino acid transporter LAT1-CD98 to control the uptake of tryptophan and AhR-dependent secretion of IL-22 by skin γδ T cells.
The activation marker CD69 is expressed by skin γδ T cells. Here we found that CD69 controlled the aryl hydrocarbon receptor (AhR)-dependent secretion of in...
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Full title
CD69 controls the uptake of L-tryptophan through LAT1-CD98 and AhR-dependent secretion of IL-22 in psoriasis
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TN_cdi_proquest_miscellaneous_1811889232
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1811889232
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.3504
