Specialized proteasome subunits have an essential role in the thymic selection of CD8 super(+) T cel...
Specialized proteasome subunits have an essential role in the thymic selection of CD8 super(+) T cells
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English
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The cells that stimulate positive selection express specialized proteasome beta -subunits different from those expressed by all other cells, including those involved in negative selection. Mice that lack all four specialized proteasome beta -subunits, and therefore express only constitutive proteasomes in all cells, had a profound defect in the gen...
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Specialized proteasome subunits have an essential role in the thymic selection of CD8 super(+) T cells
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TN_cdi_proquest_miscellaneous_1811889443
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1811889443
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ISSN
1529-2908
DOI
10.1038/ni.3480