Tyrosinemia type I and not treatment with NTBC causes slower learning and altered behavior in mice
Tyrosinemia type I and not treatment with NTBC causes slower learning and altered behavior in mice
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Publisher
Dordrecht: Springer Netherlands
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Language
English
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Publisher
Dordrecht: Springer Netherlands
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Contents
Tyrosinemia type I is a recessive inborn error of metabolism caused by mutations in the fumarylacetoacetate hydrolase (FAH) gene, coding for the final enzyme in the metabolism of tyrosine. This renders FAH nonfunctional and without treatment, toxic metabolites accumulate causing liver and kidney damage. Introduction of the drug NTBC in 2002 offered...
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Full title
Tyrosinemia type I and not treatment with NTBC causes slower learning and altered behavior in mice
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TN_cdi_proquest_miscellaneous_1815702277
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1815702277
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ISSN
0141-8955
E-ISSN
1573-2665
DOI
10.1007/s10545-016-9949-6
