IL-22 capacitates dermal fibroblast responses to TNF in scleroderma
IL-22 capacitates dermal fibroblast responses to TNF in scleroderma
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Brembilla, Nicolò Costantino , Dufour, Aleksandra Maria , Alvarez, Montserrat , Hugues, Stéphanie , Montanari, Elisa , Truchetet, Marie-Elise , Lonati, Paola , Fontao, Lionel , Gabrielli, Armando , Vettori, Serena , Valentini, Gabriele , Boehncke, Wolf-Henning , Meroni, Pierluigi and Chizzolini, Carlo
Publisher
England: Elsevier Limited
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English
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Publisher
England: Elsevier Limited
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ObjectivesInterleukin (IL) 22 mRNA in systemic sclerosis (SSc) skin and Th22 cells in SSc peripheral blood are increased, but the role of IL-22 in fibrosis development remains poorly understood.MethodsBiopsies were obtained from the involved skin of 15 SSc, 4 morphea and 8 healthy donors (HD). The presence of IL-22+ cells in the skin was determined...
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Full title
IL-22 capacitates dermal fibroblast responses to TNF in scleroderma
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TN_cdi_proquest_miscellaneous_1815707123
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1815707123
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ISSN
0003-4967
E-ISSN
1468-2060
DOI
10.1136/annrheumdis-2015-207477