Immune-dependent distant bystander effect after adenovirus-mediated suicide gene transfer in a rat m...
Immune-dependent distant bystander effect after adenovirus-mediated suicide gene transfer in a rat model of liver colorectal metastasis
About this item
Full title
Author / Creator
Agard, C , Ligeza, C , Dupas, B , Izembart, A , El Kouri, C , Moullier, P and Ferry, N
Publisher
England: Nature Publishing Group
Journal title
Language
English
Formats
Publication information
Publisher
England: Nature Publishing Group
Subjects
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Scope and Contents
Contents
Gene transfer of the herpes simplex virus thymidine kinase (HSV-tk) gene sensitizes tumor cells to the toxic effect of ganciclovir (GCV). The toxic effect of GCV extends to nontransduced surrounding cells by a metabolic process known as the bystander effect. A distant bystander effect, which involves anatomically separated tumors, has been reported...
Alternative Titles
Full title
Immune-dependent distant bystander effect after adenovirus-mediated suicide gene transfer in a rat model of liver colorectal metastasis
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_18176243
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_18176243
Other Identifiers
ISSN
0929-1903
E-ISSN
1476-5500
DOI
10.1038/sj.cgt.7700281
