Potent organo-osmium compound shifts metabolism in epithelial ovarian cancer cells
Potent organo-osmium compound shifts metabolism in epithelial ovarian cancer cells
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Platinum-based metallodrugs are the most widely used anticancer agents. Their reduced effectiveness after repeat dosing (resistance) constitutes a major clinical problem. We study a potent organo-osmium compound with improved activity over cisplatin and no cross-resistance in platinum-resistant cancers. This compound disrupts metabolism in A2780 hu...
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Full title
Potent organo-osmium compound shifts metabolism in epithelial ovarian cancer cells
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Record Identifier
TN_cdi_proquest_miscellaneous_1817829098
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1817829098
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1500925112
