Silencing porcine genes significantly reduces human-anti-pig cytotoxicity profiles: an alternative t...
Silencing porcine genes significantly reduces human-anti-pig cytotoxicity profiles: an alternative to direct complement regulation
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Cham: Springer International Publishing
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Language
English
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Cham: Springer International Publishing
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Contents
The future of solid organ transplantation is challenged by an increasing shortage of available allografts. Xenotransplantation of genetically modified porcine organs offers an answer to this problem. Strategies of genetic modification have ‘humanized’ the porcine model towards clinical relevance. Most notably, these approaches have aimed at either...
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Full title
Silencing porcine genes significantly reduces human-anti-pig cytotoxicity profiles: an alternative to direct complement regulation
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TN_cdi_proquest_miscellaneous_1820599116
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1820599116
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ISSN
0962-8819
E-ISSN
1573-9368
DOI
10.1007/s11248-016-9958-0
