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N-Glycosylation Design and Control of Therapeutic Monoclonal Antibodies

N-Glycosylation Design and Control of Therapeutic Monoclonal Antibodies

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1823459048

N-Glycosylation Design and Control of Therapeutic Monoclonal Antibodies

About this item

Full title

N-Glycosylation Design and Control of Therapeutic Monoclonal Antibodies

Publisher

England: Elsevier Ltd

Journal title

Trends in biotechnology (Regular ed.), 2016-10, Vol.34 (10), p.835-846

Language

English

Formats

Publication information

Publisher

England: Elsevier Ltd

More information

Scope and Contents

Contents

The N-linked glycan profiles on recombinant monoclonal antibody therapeutics significantly affect antibody biological functions and are largely determined by host cell genotypes and culture conditions. A key step in bioprocess development for monoclonal antibodies (mAbs) involves optimization and control of N-glycan profiles. With pressure from pri...

Alternative Titles

Full title

N-Glycosylation Design and Control of Therapeutic Monoclonal Antibodies

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1823459048

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1823459048

Other Identifiers

ISSN

0167-7799

E-ISSN

1879-3096

DOI

10.1016/j.tibtech.2016.02.013

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