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Dual antiplatelet and anticoagulant APAC prevents experimental ischemia–reperfusion-induced acute ki...

Dual antiplatelet and anticoagulant APAC prevents experimental ischemia–reperfusion-induced acute ki...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1826718792

Dual antiplatelet and anticoagulant APAC prevents experimental ischemia–reperfusion-induced acute kidney injury

About this item

Full title

Dual antiplatelet and anticoagulant APAC prevents experimental ischemia–reperfusion-induced acute kidney injury

Publisher

Tokyo: Springer Japan

Journal title

Clinical and experimental nephrology, 2017-06, Vol.21 (3), p.436-445

Language

English

Formats

Publication information

Publisher

Tokyo: Springer Japan

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Background
Renal ischemia–reperfusion predisposes to acute kidney injury (AKI) and mortality. APAC, mast cell heparin proteoglycan mimetic is a potent dual antiplatelet and anticoagulant inhibiting thrombosis in several vascular models.
Methods
Clinically relevant (0.06 and 0.13 mg/kg) and high (0.32 and 7.3 mg/kg) heparin doses of APAC an...

Alternative Titles

Full title

Dual antiplatelet and anticoagulant APAC prevents experimental ischemia–reperfusion-induced acute kidney injury

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1826718792

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1826718792

Other Identifiers

ISSN

1342-1751

E-ISSN

1437-7799

DOI

10.1007/s10157-016-1308-2

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