Trifluridine/Tipiracil: A Review in Metastatic Colorectal Cancer
Trifluridine/Tipiracil: A Review in Metastatic Colorectal Cancer
About this item
Full title
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Publisher
Cham: Springer International Publishing
Journal title
Language
English
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Publisher
Cham: Springer International Publishing
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Scope and Contents
Contents
Trifluridine/tipiracil (Lonsurf
®
) is a novel, orally active, antimetabolite agent comprised of trifluridine, a thymidine-based nucleoside analogue, and tipiracil, a potent thymidine phosphorylase inhibitor. Trifluridine is incorporated into DNA via phosphorylation, ultimately inhibiting cell proliferation. Tipiracil increases systemic expos...
Alternative Titles
Full title
Trifluridine/Tipiracil: A Review in Metastatic Colorectal Cancer
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_1827888429
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1827888429
Other Identifiers
ISSN
0012-6667
E-ISSN
1179-1950
DOI
10.1007/s40265-016-0633-9
