The Recombinant BCG ΔureC∷hly Vaccine Targets the AIM2 Inflammasome to Induce Autophagy and Inflamma...
The Recombinant BCG ΔureC∷hly Vaccine Targets the AIM2 Inflammasome to Induce Autophagy and Inflammation
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United States: Oxford University Press
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English
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United States: Oxford University Press
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Background. The recombinant BCG ΔureC::hly (rBCG) vaccine candidate induces improved protection against tuberculosis over parental BCG (pBCG) in predinical studies and has successfully completed a phase 2a clinical trial. However, the mechanisms responsible for the superior vaccine efficacy of rBCG are still incompletely understood. Here, we invest...
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The Recombinant BCG ΔureC∷hly Vaccine Targets the AIM2 Inflammasome to Induce Autophagy and Inflammation
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TN_cdi_proquest_miscellaneous_1827890099
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1827890099
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ISSN
0022-1899
E-ISSN
1537-6613
DOI
10.1093/infdis/jiu675