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The Recombinant BCG ΔureC∷hly Vaccine Targets the AIM2 Inflammasome to Induce Autophagy and Inflamma...

The Recombinant BCG ΔureC∷hly Vaccine Targets the AIM2 Inflammasome to Induce Autophagy and Inflamma...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1827890099

The Recombinant BCG ΔureC∷hly Vaccine Targets the AIM2 Inflammasome to Induce Autophagy and Inflammation

About this item

Full title

The Recombinant BCG ΔureC∷hly Vaccine Targets the AIM2 Inflammasome to Induce Autophagy and Inflammation

Publisher

United States: Oxford University Press

Journal title

The Journal of infectious diseases, 2015-06, Vol.211 (11), p.1831-1841

Language

English

Formats

Publication information

Publisher

United States: Oxford University Press

More information

Scope and Contents

Contents

Background. The recombinant BCG ΔureC::hly (rBCG) vaccine candidate induces improved protection against tuberculosis over parental BCG (pBCG) in predinical studies and has successfully completed a phase 2a clinical trial. However, the mechanisms responsible for the superior vaccine efficacy of rBCG are still incompletely understood. Here, we invest...

Alternative Titles

Full title

The Recombinant BCG ΔureC∷hly Vaccine Targets the AIM2 Inflammasome to Induce Autophagy and Inflammation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1827890099

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1827890099

Other Identifiers

ISSN

0022-1899

E-ISSN

1537-6613

DOI

10.1093/infdis/jiu675

How to access this item