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The type 2 diabetes presumed causal variant within TCF7L2 resides in an element that controls the ex...

The type 2 diabetes presumed causal variant within TCF7L2 resides in an element that controls the ex...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1827932044

The type 2 diabetes presumed causal variant within TCF7L2 resides in an element that controls the expression of ACSL5

About this item

Full title

The type 2 diabetes presumed causal variant within TCF7L2 resides in an element that controls the expression of ACSL5

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Diabetologia, 2016-11, Vol.59 (11), p.2360-2368

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Aims/hypothesis
One of the most strongly associated type 2 diabetes loci reported to date resides within the
TCF7L2
gene. Previous studies point to the T allele of rs7903146 in intron 3 as the causal variant at this locus. We aimed to identify the actual gene(s) under the influence of this variant.
Methods
Using clustered regularly i...

Alternative Titles

Full title

The type 2 diabetes presumed causal variant within TCF7L2 resides in an element that controls the expression of ACSL5

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1827932044

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1827932044

Other Identifiers

ISSN

0012-186X

E-ISSN

1432-0428

DOI

10.1007/s00125-016-4077-2

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