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Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aort...

Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aort...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1835001934

Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros

About this item

Full title

Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros

Publisher

New York: Nature Publishing Group US

Journal title

Nature biotechnology, 2016-11, Vol.34 (11), p.1168-1179

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Human embryonic stem cells are differentiated to cells similar to the embryonic aorta-gonad-mesonephros, which gives rise to hematopoietic stem cells.
The ability to generate hematopoietic stem cells from human pluripotent cells would enable many biomedical applications. We find that hematopoietic CD34
+
cells in spin embryoid bodies deriv...

Alternative Titles

Full title

Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1835001934

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1835001934

Other Identifiers

ISSN

1087-0156

E-ISSN

1546-1696

DOI

10.1038/nbt.3702

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