Carboxyl-terminal domain characterization of polyene-specific P450 hydroxylase in Pseudonocardia aut...
Carboxyl-terminal domain characterization of polyene-specific P450 hydroxylase in Pseudonocardia autotrophica
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Berlin/Heidelberg: Oxford University Press
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Language
English
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Berlin/Heidelberg: Oxford University Press
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Abstract
A polyene compound NPP identified in Pseudonocardia autotrophica was shown to contain an aglycone identical to nystatin, but to harbor a unique disaccharide moiety that led to higher solubility and reduced hemolytic activity. Recently, it was revealed that the final step of NPP (nystatin-like polyene) biosynthesis is C10 regio-specific...
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Full title
Carboxyl-terminal domain characterization of polyene-specific P450 hydroxylase in Pseudonocardia autotrophica
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TN_cdi_proquest_miscellaneous_1835430040
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1835430040
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ISSN
1367-5435
E-ISSN
1476-5535
DOI
10.1007/s10295-016-1813-z
