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Experimental Evidence that 3-Methylglutaric Acid Disturbs Mitochondrial Function and Induced Oxidati...

Experimental Evidence that 3-Methylglutaric Acid Disturbs Mitochondrial Function and Induced Oxidati...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1837293583

Experimental Evidence that 3-Methylglutaric Acid Disturbs Mitochondrial Function and Induced Oxidative Stress in Rat Brain Synaptosomes: New Converging Mechanisms

About this item

Full title

Experimental Evidence that 3-Methylglutaric Acid Disturbs Mitochondrial Function and Induced Oxidative Stress in Rat Brain Synaptosomes: New Converging Mechanisms

Publisher

New York: Springer US

Journal title

Neurochemical research, 2016-10, Vol.41 (10), p.2619-2626

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

3-Methylglutaric acid (3MGA) is an organic acid that accumulates in various organic acidemias whose patients present neurodegeneration events in children coursing with metabolic acidurias. Limited evidence describes the toxic mechanisms elicited by 3MGA in the brain. Herein, we explored the effects of 3MGA on different toxic endpoints in synaptosom...

Alternative Titles

Full title

Experimental Evidence that 3-Methylglutaric Acid Disturbs Mitochondrial Function and Induced Oxidative Stress in Rat Brain Synaptosomes: New Converging Mechanisms

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1837293583

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1837293583

Other Identifiers

ISSN

0364-3190

E-ISSN

1573-6903

DOI

10.1007/s11064-016-1973-2

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