A bacterial genetic selection system for ubiquitylation cascade discovery
A bacterial genetic selection system for ubiquitylation cascade discovery
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New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
An
Escherichia coli
-based genetic selection system, constructed from a split antibiotic resistance protein individually tethered to ubiquitin and a target protein, helps discover ubiquitin cascade pathway interactions.
About one-third of the eukaryotic proteome undergoes ubiquitylation, but the enzymatic cascades leading to substrate modi...
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A bacterial genetic selection system for ubiquitylation cascade discovery
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TN_cdi_proquest_miscellaneous_1837309817
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1837309817
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ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/nmeth.4003
