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Exogenous Hsp70 delays senescence and improves cognitive function in aging mice

Exogenous Hsp70 delays senescence and improves cognitive function in aging mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1837317379

Exogenous Hsp70 delays senescence and improves cognitive function in aging mice

About this item

Full title

Exogenous Hsp70 delays senescence and improves cognitive function in aging mice

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (52), p.16006-16011

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Molecular chaperone Heat Shock Protein 70 (Hsp70) plays an important protective role in various neurodegenerative disorders often associated with aging, but its activity and availability in neuronal tissue decrease with age. Here we explored the effects of intranasal administration of exogenous recombinant human Hsp70 (eHsp70) on lifespan and neuro...

Alternative Titles

Full title

Exogenous Hsp70 delays senescence and improves cognitive function in aging mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1837317379

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1837317379

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1516131112

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