The role of protein dynamics in the evolution of new enzyme function
The role of protein dynamics in the evolution of new enzyme function
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Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Analysis of the structures and dynamics of intermediates and engineered mutants from directed protein evolution experiments reveals how dynamic conformational changes are harnessed across evolutionary trajectories to generate new catalytic functions.
Enzymes must be ordered to allow the stabilization of transition states by their active sites, y...
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Full title
The role of protein dynamics in the evolution of new enzyme function
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TN_cdi_proquest_miscellaneous_1837325465
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1837325465
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ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/nchembio.2175
