Is there new hope for therapeutic matrix metalloproteinase inhibition?
Is there new hope for therapeutic matrix metalloproteinase inhibition?
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Despite promising preclinical data supporting the blockage of MMPs as a treatment for cancer, all Phase III cancer trials failed. This might be due to inadequate clinical trial design, the characteristics of the MMP inhibitors used, poor knowledge on the complexity of the MMPs and discrepancies between the mouse models and the patient...
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Full title
Is there new hope for therapeutic matrix metalloproteinase inhibition?
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TN_cdi_proquest_miscellaneous_1842507852
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1842507852
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ISSN
1474-1776
E-ISSN
1474-1784
DOI
10.1038/nrd4390
