Liver X receptors in lipid metabolism: opportunities for drug discovery
Liver X receptors in lipid metabolism: opportunities for drug discovery
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
The liver X receptors (LXRs) are sterol-sensitive transcription factors that regulate cholesterol homeostasis.
LXRs control the expression of genes that are linked to lipid synthesis, transport and excretion in many tissues.
LXRs are crucial regulators of the reverse cholesterol transport pathway and are important determinants o...
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Full title
Liver X receptors in lipid metabolism: opportunities for drug discovery
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TN_cdi_proquest_miscellaneous_1842509452
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1842509452
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ISSN
1474-1776
E-ISSN
1474-1784
DOI
10.1038/nrd4280
