Training a model for estimating leukocyte composition using whole-blood DNA methylation and cell cou...
Training a model for estimating leukocyte composition using whole-blood DNA methylation and cell counts as reference
About this item
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Publisher
England: Future Medicine Ltd
Journal title
Language
English
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Publication information
Publisher
England: Future Medicine Ltd
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Scope and Contents
Contents
Whole-blood DNA methylation depends on the underlying leukocyte composition and confounding hereby is a major concern in epigenome-wide association studies. Cell counts are often missing or may not be feasible. Computational approaches estimate leukocyte composition from DNA methylation based on reference datasets of purified leukocytes. We explore...
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Full title
Training a model for estimating leukocyte composition using whole-blood DNA methylation and cell counts as reference
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Record Identifier
TN_cdi_proquest_miscellaneous_1844023497
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1844023497
Other Identifiers
ISSN
1750-1911,1750-192X
E-ISSN
1750-192X
DOI
10.2217/epi-2016-0091
