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A photoactivatable Cre–loxP recombination system for optogenetic genome engineering

A photoactivatable Cre–loxP recombination system for optogenetic genome engineering

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1846392642

A photoactivatable Cre–loxP recombination system for optogenetic genome engineering

About this item

Full title

A photoactivatable Cre–loxP recombination system for optogenetic genome engineering

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2016-12, Vol.12 (12), p.1059-1064

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The Cre–
loxP
recombination system is a classical tool for targeted genetic engineering. Blue-light-induced dimerization of a split Cre system enables efficient light-controlled DNA integration at
loxP
sites within cells and in living mouse tissues.
Genome engineering techniques represented by the Cre–
loxP
recombination system...

Alternative Titles

Full title

A photoactivatable Cre–loxP recombination system for optogenetic genome engineering

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1846392642

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1846392642

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/nchembio.2205

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