Krueppel-like factor 4 negatively regulates cellular antiviral immune response
Krueppel-like factor 4 negatively regulates cellular antiviral immune response
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Author / Creator
Luo, Wei-Wei , Lian, Huan , Zhong, Bo , Shu, Hong-Bing and Li, Shu
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Language
English
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Contents
Viral infection triggers activation of the transcription factors NF- Kappa B and IRF3, which collaborate to induce the expression of type I interferons (IFNs) and elicit innate antiviral response. In this report, we identified Krueppel-like factor 4 (KLF4) as a negative regulator of virus-triggered signaling. Overexpression of KLF4 inhibited virus-...
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Full title
Krueppel-like factor 4 negatively regulates cellular antiviral immune response
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TN_cdi_proquest_miscellaneous_1846393052
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1846393052
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ISSN
1672-7681
DOI
10.1038/cmi.2014.125
