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Curcumin analog EF24 induces apoptosis via ROS-dependent mitochondrial dysfunction in human colorect...

Curcumin analog EF24 induces apoptosis via ROS-dependent mitochondrial dysfunction in human colorect...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1846420705

Curcumin analog EF24 induces apoptosis via ROS-dependent mitochondrial dysfunction in human colorectal cancer cells

About this item

Full title

Curcumin analog EF24 induces apoptosis via ROS-dependent mitochondrial dysfunction in human colorectal cancer cells

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Cancer chemotherapy and pharmacology, 2016-12, Vol.78 (6), p.1151-1161

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Purpose
Colorectal cancer is the most commonly diagnosed malignancy with high mortality rates worldwide. Improved therapeutic strategies with minimal adverse side effects are urgently needed. In this study, the anti-tumor effects of EF24, a novel analog of the natural compound curcumin, were evaluated in colorectal cancer cells.
Methods
Th...

Alternative Titles

Full title

Curcumin analog EF24 induces apoptosis via ROS-dependent mitochondrial dysfunction in human colorectal cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1846420705

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1846420705

Other Identifiers

ISSN

0344-5704

E-ISSN

1432-0843

DOI

10.1007/s00280-016-3172-x

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